Several genetic variations may affect belly fat accumulation. Genetics is merely one of several factors that affect body fat distribution. Lifestyle, diet, and environment also matter. The following genetic variations increase abdominal fat:
FTO Gene (Fat Mass and Obesity-Associated Gene): – The FTO gene has been extensively studied and is associated with body mass index (BMI) and obesity.
MC4R Gene (Melanocortin 4 Receptor): – The MC4R gene is involved in appetite regulation and energy balance.
PPARG Gene (Peroxisome Proliferator-Activated Receptor Gamma): – The PPARG gene plays a role in adipocyte (fat cell) differentiation and function.
ADIPOQ Gene (Adiponectin): – Adiponectin is a hormone involved in regulating glucose levels and fatty acid breakdown.
APOA2 Gene (Apolipoprotein A-II): – The APOA2 gene is involved in lipid metabolism.
LPL Gene (Lipoprotein Lipase): – Lipoprotein lipase is an enzyme that plays a role in lipid metabolism.
Genetics and obesity study may uncover more genetic variants and illuminate the intricate link between genetics and body fat distribution.
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